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Potential Role for CA-SP in Nucleating Retroviral Capsid Maturation

During virion maturation, the Rous sarcoma virus (RSV) capsid protein is cleaved from the Gag protein as the proteolytic intermediate CA-SP. Further trimming at two C-terminal sites removes the spacer peptide (SP), producing the mature capsid proteins CA and CA-S. Abundant genetic and structural evi...

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Detalhes bibliográficos
Main Authors: England, Matthew R., Purdy, John G., Ropson, Ira J., Dalessio, Paula M., Craven, Rebecca C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054415/
https://ncbi.nlm.nih.gov/pubmed/24719425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00309-14
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