Neutrophil Depletion Suppresses Pulmonary Vascular Hyperpermeability and Occurrence of Pulmonary Edema Caused by Hantavirus Infection in C.B-17 SCID Mice

Hantavirus infections are characterized by vascular hyperpermeability and neutrophilia. However, the pathogenesis of this disease is poorly understood. Here, we demonstrate for the first time that pulmonary vascular permeability is increased by Hantaan virus infection and results in the development...

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Main Authors: Koma, Takaaki, Yoshimatsu, Kumiko, Nagata, Noriyo, Sato, Yuko, Shimizu, Kenta, Yasuda, Shumpei P., Amada, Takako, Nishio, Sanae, Hasegawa, Hideki, Arikawa, Jiro
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054411/
https://ncbi.nlm.nih.gov/pubmed/24719427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00254-14
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