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Appearance of renal hemorrhage in adult mice after inoculation of patient-derived hantavirus

BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) caused by hantavirus infection is characterized by fever, renal dysfunction and hemorrhage. An animal model mimicking symptoms of HFRS remains to be established. In this study, we evaluated the pathogenicity of an HFRS patient-derived Hantaan...

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Dettagli Bibliografici
Pubblicato in:Virol J
Autori principali: Shimizu, Kenta, Koma, Takaaki, Yoshimatsu, Kumiko, Tsuda, Yoshimi, Isegawa, Yuji, Arikawa, Jiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267462/
https://ncbi.nlm.nih.gov/pubmed/28122569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0686-8
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