Appearance of renal hemorrhage in adult mice after inoculation of patient-derived hantavirus

BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) caused by hantavirus infection is characterized by fever, renal dysfunction and hemorrhage. An animal model mimicking symptoms of HFRS remains to be established. In this study, we evaluated the pathogenicity of an HFRS patient-derived Hantaan...

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Bibliographische Detailangaben
Veröffentlicht in:Virol J
Hauptverfasser: Shimizu, Kenta, Koma, Takaaki, Yoshimatsu, Kumiko, Tsuda, Yoshimi, Isegawa, Yuji, Arikawa, Jiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267462/
https://ncbi.nlm.nih.gov/pubmed/28122569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0686-8
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