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Appearance of renal hemorrhage in adult mice after inoculation of patient-derived hantavirus

BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) caused by hantavirus infection is characterized by fever, renal dysfunction and hemorrhage. An animal model mimicking symptoms of HFRS remains to be established. In this study, we evaluated the pathogenicity of an HFRS patient-derived Hantaan...

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Detalhes bibliográficos
Publicado no:Virol J
Main Authors: Shimizu, Kenta, Koma, Takaaki, Yoshimatsu, Kumiko, Tsuda, Yoshimi, Isegawa, Yuji, Arikawa, Jiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5267462/
https://ncbi.nlm.nih.gov/pubmed/28122569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0686-8
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