Neutrophil Depletion Suppresses Pulmonary Vascular Hyperpermeability and Occurrence of Pulmonary Edema Caused by Hantavirus Infection in C.B-17 SCID Mice

Hantavirus infections are characterized by vascular hyperpermeability and neutrophilia. However, the pathogenesis of this disease is poorly understood. Here, we demonstrate for the first time that pulmonary vascular permeability is increased by Hantaan virus infection and results in the development...

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Главные авторы: Koma, Takaaki, Yoshimatsu, Kumiko, Nagata, Noriyo, Sato, Yuko, Shimizu, Kenta, Yasuda, Shumpei P., Amada, Takako, Nishio, Sanae, Hasegawa, Hideki, Arikawa, Jiro
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
Предметы:
Pathogenesis and Immunity
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054411/
https://ncbi.nlm.nih.gov/pubmed/24719427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00254-14
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