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Muscarinic acetylcholine receptor down-regulation limits the extent of inhibition of cell cycle progression in Chinese hamster ovary cells.

Cellular desensitization is believed to be important for growth control but direct evidence is lacking. In the current study we compared effects of wild-type and down-regulation-resistant mutant m3 muscarinic receptors on Chinese hamster ovary (CHO-K1) cell desensitization, proliferation, and transf...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Detjen, K, Yang, J, Logsdon, C D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40544/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.10929
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