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Carbachol-Induced Secretion and Homologous Desensitization in Rat Basophilic Leukemia (RBL-2H3) Cells Transfected With Human m2 Muscarinic Acetylcholine Receptors

Carbachol (CCh) caused a dose-dependent release of β-hexosaminidase and an increase in the production of inositol 1,4,5-trisphosphate (IP3) in RBL-2H3 cells transfected with m2 mAChR cDNA (RBL-m2 cells). The secretion was completely inhibited by LaCl3 and pertussis toxin. The secretion was dependent...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kazuhiko Oishi, Akihiro Sakurai, Noriyasu Seki, Tomokazu Yoshizumi, Masaatsu K. Uchida
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2004-01-01
Cyfres:Journal of Pharmacological Sciences
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S1347861319323795
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