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Alternative Recognition of the Conserved Stem Epitope in Influenza A Virus Hemagglutinin by a V(H)3-30-Encoded Heterosubtypic Antibody
A human monoclonal heterosubtypic antibody, MAb 3.1, with its heavy chain encoded by V(H)3-30, was isolated using phage display with immobilized hemagglutinin (HA) from influenza virus A/Japan/305/1957(H2N2) as the target. Antibody 3.1 potently neutralizes influenza viruses from the H1a clade (i.e.,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054347/ https://ncbi.nlm.nih.gov/pubmed/24719426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00178-14 |
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