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Heterosubtypic Antibodies to Influenza A Virus Have Limited Activity against Cell-Bound Virus but Are Not Impaired by Strain-Specific Serum Antibodies

The majority of influenza virus-specific antibodies elicited by vaccination or natural infection are effective only against the eliciting or closely related viruses. Rare stem-specific heterosubtypic monoclonal antibodies (hMAbs) can neutralize multiple strains and subtypes by preventing hemagglutin...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wyrzucki, Arkadiusz, Bianchi, Matteo, Kohler, Ines, Steck, Marco, Hangartner, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4337524/
https://ncbi.nlm.nih.gov/pubmed/25552718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03069-14
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