STAT1β Is Not Dominant Negative and Is Capable of Contributing to Gamma Interferon-Dependent Innate Immunity

The transcription factor STAT1 is essential for interferon (IFN)-mediated immunity in humans and mice. STAT1 function is tightly regulated, and both loss- and gain-of-function mutations result in severe immune diseases. The two alternatively spliced isoforms, STAT1α and STAT1β, differ with regard to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Semper, Christian, Leitner, Nicole R., Lassnig, Caroline, Parrini, Matthias, Mahlakõiv, Tanel, Rammerstorfer, Michael, Lorenz, Karin, Rigler, Doris, Müller, Simone, Kolbe, Thomas, Vogl, Claus, Rülicke, Thomas, Staeheli, Peter, Decker, Thomas, Müller, Mathias, Strobl, Birgit
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054301/
https://ncbi.nlm.nih.gov/pubmed/24710278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00295-14
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker