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A Conserved Loop in the Catalytic Domain of Eukaryotic Elongation Factor 2 Kinase Plays a Key Role in Its Substrate Specificity

Eukaryotic elongation factor 2 kinase (eEF2K) is the best-characterized member of the α-kinase family. Within this group, only eEF2K and myosin heavy chain kinases (MHCKs) have known substrates. Here we have studied the roles of specific residues, selected on the basis of structural data for MHCK A...

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Detalhes bibliográficos
Main Authors: Moore, Claire E., Regufe da Mota, Sergio, Mikolajek, Halina, Proud, Christopher G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054288/
https://ncbi.nlm.nih.gov/pubmed/24732796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00388-14
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