Eukaryotic Elongation Factor 2 Kinase Activity Is Controlled by Multiple Inputs from Oncogenic Signaling

Eukaryotic elongation factor 2 kinase (eEF2K), an atypical calmodulin-dependent protein kinase, phosphorylates and inhibits eEF2, slowing down translation elongation. eEF2K contains an N-terminal catalytic domain, a C-terminal α-helical region and a linker containing several regulatory phosphorylati...

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Publicado en:Mol Cell Biol
Autores principales: Wang, Xuemin, Regufe da Mota, Sergio, Liu, Rui, Moore, Claire E., Xie, Jianling, Lanucara, Francesco, Agarwala, Usha, Pyr dit Ruys, Sébastien, Vertommen, Didier, Rider, Mark H., Eyers, Claire E., Proud, Christopher G.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248706/
https://ncbi.nlm.nih.gov/pubmed/25182533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01035-14
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