Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

BACKGROUND: DNA methylation is an epigenetic modification that changes with age in human tissues, although the mechanisms and specificity of this process are still poorly understood. We compared CpG methylation changes with age across 283 human blood, brain, kidney, and skeletal muscle samples using...

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Detalhes bibliográficos
Main Authors: Day, Kenneth, Waite, Lindsay L, Thalacker-Mercer, Anna, West, Andrew, Bamman, Marcas M, Brooks, James D, Myers, Richard M, Absher, Devin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053985/
https://ncbi.nlm.nih.gov/pubmed/24034465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-9-r102
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