PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs

The regulation of intragenic miRNAs by their own intronic promoters is one of the open problems of miRNA biogenesis. Here, we describe PROmiRNA, a new approach for miRNA promoter annotation based on a semi-supervised statistical model trained on deepCAGE data and sequence features. We validate our r...

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Autors principals: Marsico, Annalisa, Huska, Matthew R, Lasserre, Julia, Hu, Haiyang, Vucicevic, Dubravka, Musahl, Anne, Orom, Ulf Andersson, Vingron, Martin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053815/
https://ncbi.nlm.nih.gov/pubmed/23958307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-8-r84
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