PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs

The regulation of intragenic miRNAs by their own intronic promoters is one of the open problems of miRNA biogenesis. Here, we describe PROmiRNA, a new approach for miRNA promoter annotation based on a semi-supervised statistical model trained on deepCAGE data and sequence features. We validate our r...

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Detaylı Bibliyografya
Asıl Yazarlar: Marsico, Annalisa, Huska, Matthew R, Lasserre, Julia, Hu, Haiyang, Vucicevic, Dubravka, Musahl, Anne, Orom, Ulf Andersson, Vingron, Martin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053815/
https://ncbi.nlm.nih.gov/pubmed/23958307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-8-r84
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