PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs

The regulation of intragenic miRNAs by their own intronic promoters is one of the open problems of miRNA biogenesis. Here, we describe PROmiRNA, a new approach for miRNA promoter annotation based on a semi-supervised statistical model trained on deepCAGE data and sequence features. We validate our r...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Marsico, Annalisa, Huska, Matthew R, Lasserre, Julia, Hu, Haiyang, Vucicevic, Dubravka, Musahl, Anne, Orom, Ulf Andersson, Vingron, Martin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Method
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053815/
https://ncbi.nlm.nih.gov/pubmed/23958307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-8-r84
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