PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs

The regulation of intragenic miRNAs by their own intronic promoters is one of the open problems of miRNA biogenesis. Here, we describe PROmiRNA, a new approach for miRNA promoter annotation based on a semi-supervised statistical model trained on deepCAGE data and sequence features. We validate our r...

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Dettagli Bibliografici
Autori principali: Marsico, Annalisa, Huska, Matthew R, Lasserre, Julia, Hu, Haiyang, Vucicevic, Dubravka, Musahl, Anne, Orom, Ulf Andersson, Vingron, Martin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Method
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053815/
https://ncbi.nlm.nih.gov/pubmed/23958307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-8-r84
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