PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs

The regulation of intragenic miRNAs by their own intronic promoters is one of the open problems of miRNA biogenesis. Here, we describe PROmiRNA, a new approach for miRNA promoter annotation based on a semi-supervised statistical model trained on deepCAGE data and sequence features. We validate our r...

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Detalhes bibliográficos
Main Authors: Marsico, Annalisa, Huska, Matthew R, Lasserre, Julia, Hu, Haiyang, Vucicevic, Dubravka, Musahl, Anne, Orom, Ulf Andersson, Vingron, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053815/
https://ncbi.nlm.nih.gov/pubmed/23958307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-8-r84
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