p53 induces transcriptional and translational programs to suppress cell proliferation and growth

BACKGROUND: Cell growth and proliferation are tightly connected to ensure that appropriately sized daughter cells are generated following mitosis. Energy stress blocks cell growth and proliferation, a critical response for survival under extreme conditions. Excessive oncogenic stress leads to p53 ac...

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Bibliographic Details
Main Authors: Loayza-Puch, Fabricio, Drost, Jarno, Rooijers, Koos, Lopes, Rui, Elkon, Ran, Agami, Reuven
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053767/
https://ncbi.nlm.nih.gov/pubmed/23594524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-4-r32
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