Myc coordinates transcription and translation to enhance transformation and suppress invasiveness

c‐Myc is one of the major human proto‐oncogenes and is often associated with tumor aggression and poor clinical outcome. Paradoxically, Myc was also reported as a suppressor of cell motility, invasiveness, and metastasis. Among the direct targets of Myc are many components of the protein synthesis m...

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Udgivet i:EMBO Rep
Main Authors: Elkon, Ran, Loayza‐Puch, Fabricio, Korkmaz, Gozde, Lopes, Rui, van Breugel, Pieter C, Bleijerveld, Onno B, Altelaar, AF Maarten, Wolf, Elmar, Lorenzin, Francesca, Eilers, Martin, Agami, Reuven
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687422/
https://ncbi.nlm.nih.gov/pubmed/26538417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540717
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