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KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation
BACKGROUND: Pluripotency of embryonic stem (ES) cells is controlled in part by chromatin-modifying factors that regulate histone H3 lysine 4 (H3K4) methylation. However, it remains unclear how H3K4 demethylation contributes to ES cell function. RESULTS: Here, we show that KDM5B, which demethylates l...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053761/ https://ncbi.nlm.nih.gov/pubmed/24495580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-2-r32 |
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