FOXO1 is an essential regulator of pluripotency in human embryonic stem cells

Pluripotency of embryonic stem cells (ESCs) is defined by their ability to differentiate into three germ layers and derivative cell types(1-3) and is established by an interactive network of proteins including OCT4 (also known as POU5F1; ref. 4), NANOG (refs 5,6), SOX2 (ref. 7) and their binding par...

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Główni autorzy: Zhang, Xin, Yalcin, Safak, Lee, Dung-Fang, Yeh, Tsung-Yin J., Lee, Seung-Min, Su, Jie, Mungamuri, Sathish Kumar, Rimmelé, Pauline, Kennedy, Marion, Sellers, Rani, Landthaler, Markus, Tuschl, Thomas, Chi, Nai-Wen, Lemischka, Ihor, Keller, Gordon, Ghaffari, Saghi
Format: Artigo
Język:Inglês
Wydane: 2011
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Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053529/
https://ncbi.nlm.nih.gov/pubmed/21804543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2293
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