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Bexarotene reduces network excitability in models of Alzheimer’s disease and epilepsy
The nuclear retinoid X receptor (RXR) agonist, bexarotene, has been implicated in recovery of cognitive function in mouse models of Alzheimer’s disease. Since AD genetic mouse models also show abnormal neural hyperexcitability, which may play a destructive role in memory storage and retrieval, we st...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053509/ https://ncbi.nlm.nih.gov/pubmed/24767949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.03.029 |
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