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Altering neuronal excitability to preserve network connectivity in a computational model of Alzheimer's disease
Neuronal hyperactivity and hyperexcitability of the cerebral cortex and hippocampal region is an increasingly observed phenomenon in preclinical Alzheimer’s disease (AD). In later stages, oscillatory slowing and loss of functional connectivity are ubiquitous. Recent evidence suggests that neuronal d...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5627940/ https://ncbi.nlm.nih.gov/pubmed/28938009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005707 |
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