METFORMIN: an efficacy, safety and pharmacokinetic study on the short-term and long-term use in obese children and adolescents – study protocol of a randomized controlled study

BACKGROUND: The prevalence of childhood obesity and insulin resistance is rising, increasing the risk of diabetes mellitus type 2. To prevent these complications, lifestyle intervention is the corner stone in treatment. However, long-term efficacy of lifestyle intervention is questionable. In additi...

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Hlavní autoři: van der Aa, Marloes P, Elst, Marieke AJ, van Mil, Edgar GAH, Knibbe, Catherijne AJ, van der Vorst, Marja MJ
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Study Protocol
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053305/
https://ncbi.nlm.nih.gov/pubmed/24899137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6215-15-207
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