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MEK inhibition as a strategy for targeting residual breast cancer cells with low DUSP4 expression

Lack of eradication of disseminated breast cancer by chemotherapy is a central clinical problem. Even tumors that show substantial shrinkage after drug treatment frequently relapse and eventually become refractory to all drugs available. The mechanisms underlying this lack of eradication are largely...

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Hlavní autoři: Rottenberg, Sven, Jonkers, Jos
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053122/
https://ncbi.nlm.nih.gov/pubmed/23127286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3327
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