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MEK inhibition as a strategy for targeting residual breast cancer cells with low DUSP4 expression

Lack of eradication of disseminated breast cancer by chemotherapy is a central clinical problem. Even tumors that show substantial shrinkage after drug treatment frequently relapse and eventually become refractory to all drugs available. The mechanisms underlying this lack of eradication are largely...

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Detalhes bibliográficos
Main Authors: Rottenberg, Sven, Jonkers, Jos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053122/
https://ncbi.nlm.nih.gov/pubmed/23127286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3327
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