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‘Doubling down’ on the autophagy pathway to suppress tumor growth

In this issue of Genes & Development, Wei and colleagues (pp. 1204–1216) use elegant genetic approaches to simultaneously delete the essential autophagy gene FIP200 (FAK family-interacting protein of 200 kDa) and the signaling adaptor p62/SQSTM1 within established murine tumors, which reveals an...

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Detalhes bibliográficos
Main Authors: Leidal, Andrew M., Debnath, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052759/
https://ncbi.nlm.nih.gov/pubmed/24888584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.244681.114
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