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‘Doubling down’ on the autophagy pathway to suppress tumor growth
In this issue of Genes & Development, Wei and colleagues (pp. 1204–1216) use elegant genetic approaches to simultaneously delete the essential autophagy gene FIP200 (FAK family-interacting protein of 200 kDa) and the signaling adaptor p62/SQSTM1 within established murine tumors, which reveals an...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052759/ https://ncbi.nlm.nih.gov/pubmed/24888584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.244681.114 |
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