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Autophagy dependent production of secreted factors facilitates oncogenic RAS-driven invasion

The tumor promoting functions of autophagy are primarily attributed to its ability to promote cancer cell survival. However, emerging evidence suggests that autophagy plays other roles during tumorigenesis. Here, we uncover that autophagy promotes oncogenic RAS-driven invasion. In epithelial cells t...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lock, Rebecca, Kenific, Candia M., Leidal, Andrew M., Salas, Eduardo, Debnath, Jayanta
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980002/
https://ncbi.nlm.nih.gov/pubmed/24513958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0841
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