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Autophagy dependent production of secreted factors facilitates oncogenic RAS-driven invasion

The tumor promoting functions of autophagy are primarily attributed to its ability to promote cancer cell survival. However, emerging evidence suggests that autophagy plays other roles during tumorigenesis. Here, we uncover that autophagy promotes oncogenic RAS-driven invasion. In epithelial cells t...

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Hlavní autoři: Lock, Rebecca, Kenific, Candia M., Leidal, Andrew M., Salas, Eduardo, Debnath, Jayanta
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980002/
https://ncbi.nlm.nih.gov/pubmed/24513958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0841
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