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Autophagy dependent production of secreted factors facilitates oncogenic RAS-driven invasion

The tumor promoting functions of autophagy are primarily attributed to its ability to promote cancer cell survival. However, emerging evidence suggests that autophagy plays other roles during tumorigenesis. Here, we uncover that autophagy promotes oncogenic RAS-driven invasion. In epithelial cells t...

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Detalles Bibliográficos
Main Authors: Lock, Rebecca, Kenific, Candia M., Leidal, Andrew M., Salas, Eduardo, Debnath, Jayanta
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980002/
https://ncbi.nlm.nih.gov/pubmed/24513958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0841
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