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A Structural Model for Glutathione-Complexed Iron-Sulfur Cluster as a Substrate for ABCB7-Type Transporters
Glutathione-complexed [2Fe-2S] cluster is shown to significantly stimulate the ATPase activity of an ABCB7-type transporter in both solution and proteoliposome-bound forms (K(D) ~ 68 μM). The cluster is a likely natural substrate for this transporter, which has been implicated in cytosolic Fe-S clus...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052440/ https://ncbi.nlm.nih.gov/pubmed/24584132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc48239a |
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