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A Structural Model for Glutathione-Complexed Iron-Sulfur Cluster as a Substrate for ABCB7-Type Transporters

Glutathione-complexed [2Fe-2S] cluster is shown to significantly stimulate the ATPase activity of an ABCB7-type transporter in both solution and proteoliposome-bound forms (K(D) ~ 68 μM). The cluster is a likely natural substrate for this transporter, which has been implicated in cytosolic Fe-S clus...

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Hlavní autoři: Qi, Wenbin, Li, Jingwei, Cowan, J. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052440/
https://ncbi.nlm.nih.gov/pubmed/24584132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc48239a
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