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Glutathione-coordinated metal complexes as substrates for cellular transporters

Glutathione is the major thiol-containing species in both prokaryotes and eukaryotes and plays a wide variety of roles, including detoxification of metals by sequestration, reduction, and efflux. ABC transporters such as MRP1 and MRP2 detoxify the cell from certain metals by exporting the cations as...

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Detalhes bibliográficos
Publicado no:Metallomics
Main Authors: Pearson, Stephen A, Cowan, J A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086996/
https://ncbi.nlm.nih.gov/pubmed/33770183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mtomcs/mfab015
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