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Monocytes differentiated with GM-CSF and IL-15 initiate Th17 and Th1 responses that are contact-dependent and mediated by IL-15
Distinct types of DCs are generated from monocytes using GM-CSF with IL-4 (IL4-DC) or IL-15 (IL15-DC). IL15-DCs are potent inducers of antigen-specific CD8(+) T cells, display a phenotype similar to CD14(+) cells commonly described in chronically inflamed tissues, and produce high levels of IL-1β an...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Leukocyte Biology
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052426/ https://ncbi.nlm.nih.gov/pubmed/21724805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0311132 |
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