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Monocytes Differentiated with IL-15 Support Th17 and Th1 Responses to Wheat Gliadin: Implications for Celiac Disease

Interleukin (IL)-15 contributes to the immunopathogenesis of Celiac disease (CD). However, it is not clear how IL-15 affects APC that shape adaptive immune responses to the dietary antigen, gliadin. Using PBMC from healthy individuals, we show that monocytes differentiated with IL-15 (IL15-DC) produ...

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Detalhes bibliográficos
Main Authors: Harris, Kristina M., Fasano, Alessio, Mann, Dean L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868103/
https://ncbi.nlm.nih.gov/pubmed/20153259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.01.003
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