The Proapoptotic Protein tBid Forms Both Superficially Bound and Membrane-Inserted Oligomers

Bid is a proapopotic activator protein of the Bcl-2 family that plays a pivotal role in controlling mitochondrial outer membrane permeabilization during apoptosis. Here, we characterized the interaction of fluorescently labeled truncated Bid (tBid) with a mitochondria-like supported lipid bilayer at...

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Hlavní autoři: Shivakumar, Sanjeevan, Kurylowicz, Martin, Hirmiz, Nehad, Manan, Yaseen, Friaa, Ouided, Shamas-Din, Aisha, Masoudian, Pourya, Leber, Brian, Andrews, David W., Fradin, Cécile
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2014
Témata:
Cell Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052270/
https://ncbi.nlm.nih.gov/pubmed/24853737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.03.049
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