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Conformation of Membrane-associated Proapoptotic tBid

The proapoptotic Bcl-2 family protein Bid is cleaved by caspase-8 to release the C-terminal fragment tBid, which translocates to the outer mitochondrial membrane and induces massive cytochrome c release and cell death. In this study, we have characterized the conformation of tBid in lipid membrane e...

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Detalhes bibliográficos
Main Authors: Gong, Xiao-Min, Choi, Jungyuen, Franzin, Carla M., Zhai, Dayong, Reed, John C., Marassi, Francesca M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3033194/
https://ncbi.nlm.nih.gov/pubmed/15123718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M403490200
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