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Effects of the Protonation State of the EEEE Motif of a Bacterial Na(+)-channel on Conduction and Pore Structure
A distinctive feature of prokaryotic Na(+)-channels is the presence of four glutamate residues in their selectivity filter. In this study, how the structure of the selectivity filter, and the free-energy profile of permeating Na(+) ions are altered by the protonation state of Glu177 are analyzed. It...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052246/ https://ncbi.nlm.nih.gov/pubmed/24853746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.005 |
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