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Ion-triggered selectivity in bacterial sodium channels

Since the availability of the first crystal structure of a bacterial Na(+) channel in 2011, understanding selectivity across this family of membrane proteins has been the subject of intense research efforts. Initially, free energy calculations based on molecular dynamics simulations revealed that al...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Furini, Simone, Domene, Carmen
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003493/
https://ncbi.nlm.nih.gov/pubmed/29735669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722516115
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