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Human Dendritic Cells exhibit a pronounced type I IFN signature following Leishmania major infection that is required for IL-12 induction().

Leishmania major infected human dendritic cells (DCs) exhibit a marked induction of IL-12, ultimately promoting a robust Th1-mediated response associated with parasite killing and protective immunity. The host cell transcription machinery associated with the specific IL-12 induction observed during...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Favila, Michelle A., Geraci, Nicholas S., Zeng, Erliang, Harker, Brent, Condon, David, Cotton, Rachel N., Jayakumar, Asha, Tripathi, Vinita, McDowell, Mary Ann
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052223/
https://ncbi.nlm.nih.gov/pubmed/24808365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203230
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