Gremlin Activates the Smad Pathway Linked to Epithelial Mesenchymal Transdifferentiation in Cultured Tubular Epithelial Cells

Gremlin is a developmental gene upregulated in human chronic kidney disease and in renal cells in response to transforming growth factor-β (TGF-β). Epithelial mesenchymal transition (EMT) is one process involved in renal fibrosis. In tubular epithelial cells we have recently described that Gremlin i...

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Autors principals: Rodrigues-Diez, Raquel, Rodrigues-Diez, Raúl R., Lavoz, Carolina, Carvajal, Gisselle, Droguett, Alejandra, Garcia-Redondo, Ana B., Rodriguez, Isabel, Ortiz, Alberto, Egido, Jesús, Mezzano, Sergio, Ruiz-Ortega, Marta
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052161/
https://ncbi.nlm.nih.gov/pubmed/24949470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/802841
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