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The Natural Chemopreventive Agent Sulforaphane Inhibits STAT5 Activity

Signal transducer and activator of transcription STAT5 is an essential mediator of cytokine, growth factor and hormone signaling. While its activity is tightly regulated in normal cells, its constitutive activation directly contributes to oncogenesis and is associated to a number of hematological an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pinz, Sophia, Unser, Samy, Rascle, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051870/
https://ncbi.nlm.nih.gov/pubmed/24910998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099391
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