N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties

N-cadherin and HER2/neu were found to be co-expressed in invasive breast carcinomas. To test the contribution of N-cadherin and HER2 in mammary tumor metastasis, we targeted N-cadherin expression in the mammary epithelium of the MMTV-Neu mouse. In the context of ErbB2/Neu, N-cadherin stimulated carc...

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Main Authors: Qian, X, Anzovino, A, Kim, S, Suyama, K, Yao, J, Hulit, J, Agiostratidou, G, Chandiramani, N, McDaid, HM, Nagi, C, Cohen, HW, Phillips, GR, Norton, L, Hazan, RB
格式: Artigo
語言:Inglês
出版: 2013
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051865/
https://ncbi.nlm.nih.gov/pubmed/23975425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.310
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