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Synergistic Effects of 3D ECM and Chemogradients on Neurite Outgrowth and Guidance: A Simple Modeling and Microfluidic Framework

During nervous system development, numerous cues within the extracellular matrix microenvironment (ECM) guide the growing neurites along specific pathways to reach their intended targets. Neurite motility is controlled by extracellular signal sensing through the growth cone at the neurite tip, inclu...

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Библиографические подробности
Главные авторы: Srinivasan, Parthasarathy, Zervantonakis, Ioannis K., Kothapalli, Chandrasekhar R.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051856/
https://ncbi.nlm.nih.gov/pubmed/24914812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099640
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