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Sensitivity of Neural Stem Cell Survival, Differentiation and Neurite Outgrowth within 3D Hydrogels to Environmental Heavy Metals

We investigated the sensitivity of embryonic murine neural stem cells exposed to 10 pM – 10 μM concentrations of three heavy metals (Cd, Hg, Pb), continuously for 14 days within 3D collagen hydrogels. Critical endpoints for neurogenesis such as survival, differentiation and neurite outgrowth were as...

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Библиографические подробности
Опубликовано в: :Toxicol Lett
Главные авторы: Tasneem, Sameera, Farrell, Kurt, Lee, Moo-Yeal, Kothapalli, Chandrasekhar R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707078/
https://ncbi.nlm.nih.gov/pubmed/26621541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2015.11.021
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