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Preliminary joint X-ray and neutron protein crystallographic studies of ecDHFR complexed with folate and NADP(+)

A crystal of Escherichia coli dihydrofolate reductase (ecDHFR) complexed with folate and NADP(+) of 4 × 1.3 × 0.7 mm (3.6 mm(3)) in size was obtained by sequential application of microseeding and macroseeding. A neutron diffraction data set was collected to 2.0 Å resolution using the IMAGINE diffrac...

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Autors principals: Wan, Qun, Kovalevsky, Andrey Y., Wilson, Mark A., Bennett, Brad C., Langan, Paul, Dealwis, Chris
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051544/
https://ncbi.nlm.nih.gov/pubmed/24915100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1400942X
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