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High-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 molecules
Cyclophilin D (CypD) is a key mitochondrial target for amyloid-β-induced mitochondrial and synaptic dysfunction and is considered a potential drug target for Alzheimer’s disease. The high-resolution crystal structures of primitive orthorhombic (CypD-o) and primitive tetragonal (CypD-t) forms have be...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051522/ https://ncbi.nlm.nih.gov/pubmed/24915078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14009480 |
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