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Structural and functional characterization of human and murine C5a anaphylatoxins

Complement is an ancient part of the innate immune system that plays a pivotal role in protection against invading pathogens and helps to clear apoptotic and necrotic cells. Upon complement activation, a cascade of proteolytic events generates the complement effectors, including the anaphylatoxins C...

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Detalhes bibliográficos
Main Authors: Schatz-Jakobsen, Janus Asbjørn, Yatime, Laure, Larsen, Casper, Petersen, Steen Vang, Klos, Andreas, Andersen, Gregers Rom
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051506/
https://ncbi.nlm.nih.gov/pubmed/24914981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S139900471400844X
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