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The specificity of DNA recognition by the RAGE receptor

A recent paper by Sirois et al. in The Journal of Experimental Medicine reports that the receptor for advanced glycation end-products (RAGE) promotes uptake of DNA into endosomes and lowers the immune recognition threshold for the activation of Toll-like receptor 9. Two crystal structures suggested...

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Detalhes bibliográficos
Main Authors: Yatime, Laure, Andersen, Gregers Rom
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010895/
https://ncbi.nlm.nih.gov/pubmed/24778420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132526
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