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The specificity of DNA recognition by the RAGE receptor
A recent paper by Sirois et al. in The Journal of Experimental Medicine reports that the receptor for advanced glycation end-products (RAGE) promotes uptake of DNA into endosomes and lowers the immune recognition threshold for the activation of Toll-like receptor 9. Two crystal structures suggested...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010895/ https://ncbi.nlm.nih.gov/pubmed/24778420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132526 |
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