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The Role of the Anaphylatoxins in Health and Disease

The anaphylatoxins (AT) C3a, C5a and C5a-desArg are generally considered pro-inflammatory polypeptides generated after proteolytic cleavage of C3 and C5 in response to complement activation. Their well appreciated effector functions include chemotaxis and activation of granulocytes, mast cells and m...

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Detalhes bibliográficos
Main Authors: Klos, Andreas, Tenner, Andrea J., Johswich, Kay-Ole, Ager, Rahasson R., Reis, Edimara S., Köhl, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725201/
https://ncbi.nlm.nih.gov/pubmed/19477527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2009.04.027
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